Knots, links, and graphs in proteins

There is strong evidence that the presence of knots, links, and graphs in proteins provide functional advantages. Consequently, it is of interest to understand how proteins fold into knotted conformations. In this talk, I will discuss methods of knot theory that have been applied to study proteins. In particular, I will reference work with Isabel Darcy and Garrett Jones where we analyzed knots that are related by local moves that arise in the folding pathway of DehI protein.